学術論文(査読付英語論文) 2007年以前

  • M. Higaki, M. Kameyama, M Udagawa, Y. Yamaguchi, R. Igarashi, T. Ishihara, Y. Mizushima, Transdermal delivery of CaCO3-nanoparticles containing insulin
    Diabetes Technol Ther. 8:369-74 (2006)

    Y. Mizushima, T. Ikoma, J. Tanaka, K. Hoshi, T. Ishihara, Y. Ogawa, A. Ueno, Injectable porous hydroxyapatite microparticles as a new carrier for protein and lipophilic drugs
    J. Control. Release, 110: 260-265 (2006)

    T. Sakai, H. Kohno, S. Saito, M. Matsushima, T. Ishihara, M. Higaki, Y. Mizushima, K. Kitahara, Treatment of Experimental Autoimmune Uveoretinitis with Poly (lactic acid) Nanoparticles Encapsulating Betamethasone Phosphate
    Experimental Eye Research, 82: 657-663 (2006)

    T. Tamura, T. Kita, T. Nakagawa, T. S. Kim, T. Endo, T. Ishihara, M. Higaki, Y. Mizushima, J. Ito, Drug delivery to the cochlea using PLGA nanoparticles
    Laryngoscope, 115: 2000-2005 (2005)

    M. Higaki, T. Ishihara, N. Izumo, M. Takatsu, Y. Mizushima, Treatment of experimental arthritis with poly(D,L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate
    Ann Rheum Dis 2005; 64: 1132-1136 (2005)

    T. Ishihara, N. Izumo, M. Higaki, E. Shimada, T. Hagi, L. Mine, Y. Ogawa, and Y. Mizushima, Role of zinc in formulation of PLGA/PLA nanoparticles encapsulating betamethasone phosphate and its release profile
    J. Control. Release 105, 1-2, 68-76 (2005)

    W-J.Kim, T.Ishihara, T.Akaike, and A.Maruyama, Comb-type cationic copolymer expedites DNA strand exchange while stabilizing DNA duplex
    Chemistry 5, (7), 176-80 (2001)

    M.Nogawa, T.Ishihara, T.Akaike, and A.Maruyama, Polyethyleneimine/arabinogalactan conjugate as a hepatocyte specific gene carrier
    S.T.P. Pharma. Sciences, 11, 97-102 (2001)

    C-S.Cho, A.Kobayashi, R.Takei, T.Ishihara, A.Maruyama, and T.Akaike, Receptor-mediated cell modulator delivery to hepatocyte using nanoparticles coated with carbohydrate-carrying polymers
    Biomaterials, 22, 45-51 (2001)

    A.Maruyama, W-J.Kim, T.Ishihara, M.Ueda, H.Torigoe, A.Ferdous, and T.Akaike, Regulation of DNA function by cationic graft copolymers
    Biomaterials and Drug Delivery toward new mellenium, 175-181 (2000)

    X. Zhang, T. Ishihara and D.R. Corey, Strand Invasion by Mixed Base PNAs and PNA-Peptide Chimera
    Nucleic Acid Research, 28, 17, 3332-3338 (2000)

    A. Maruyama, T. Ishihara, J-S.Kim, S-W.Kim, T.Akaike, Design of multi-functional nanopritcles as a DNA carrier
    Colloids and Surfaces A:, 153, 439-443 (1999)

    J-U.Park, T.Ishihara, A.Kano, T.Akaike, A.Maruyama, Preparation of dendritic graft copolymer consisting of poly(L-lysine) and arabinogaractan as a hepatocyte specific DNA carrier
    Prep. Biochem. Biotech., 29, 353-370 (1999)

    T. Ishihara, and D.R. Corey, Rules for strand invasion by chemically modified oligonucleotides
    Journal of American Chemical Society, 121, 2012-2020 (1999)

    A.Maruyama, A.Ferdous, T.Ishihara, S.Asayama, J-U.Park, M.Nogawa, H.Watanabe, Y.Takei, and T.Akaike, Comb-type copolymers for controlled DNA delivery
    Nucleosides Nucleotides, 18, (6-7), 1681-2 (1999)

    A.Maruyama, H.Watanabe, A.Ferdous, M.Katoh, T.Ishihara, and T.Akaike, Characterization of inter polyelectrolyte complex between double stranded DNA and polylysine comb-type copolymer having hydrophilic side chains
    Bioconjugate Chemistry, 9, 292-299 (1998)

    A.Maruyama, T.Ishihara , and T.Akaike, A Nanoparticle DNA carrier with Poly(L-lysine) grafted Polysaccharide Copolymer and Poly(D,L-lactic acid)
    Bioconjugate Chemistry, 8, 735-742 (1998)

    A.Maruyama, M.Katoh, T.Ishihara, and T.Akaike, Comb-Type Polycations Effectively stabilize DNA Triplex
    Bioconjugate Chemistry, 8, 3-6 (1997)

    C-S.Cho, Y-I.Jeong, T.Ishihara, R.Takei, J-U.Park, K-H.Park, A.Maruyama, and T.Akaike, Simple Preparation of Nanoparticles coated with carbohydrate-carrying Polymers
    Biomaterials, 18, 323-326 (1997)

    N.Adachi, A.Maruyama, T.Ishihara, and T.Akaike, Cellular Distribution of Polymer Particles bearing various densities of carbohydrate ligands
    J. Biomater. Sci. Polymer Edn., 6, 463-479 (1994)

    A.Maruyama, T.Ishihara, N.Adachi, and T.Akaike, Preparation of Nanoparticles Bearing High Density of Carbohydrate Chains Using Carbohydrate Carrying Polymers as an Emulsifier
    Biomaterials, 15, 13, 1035-1042 (1994)